CrossSearch: Protein Crosslinking Prediction Server CrossSearch Protein Crosslinking Prediction Tool

Automated Prediction of Crosslinked Protein Fragments based on Theoretical Crosslink Chemistry and Experimental Mass Spectrometry Results

Developed at the University of Missouri-Kansas City Division of Molecular Biology and Biochemistry

and the
Kansas University Medical Center-Department of Biochemistry and Molecular Biology


Open existing project file

Start a new Project
Enter a your name or other personal identifier
you will need to remember this to access your results in the future (e-mail is a good option)
Input Protein Sequences: 
Input Amino Acid Sequence Only
Protein 1:

Protein 2:

Input Target Experimental Masses: 
Masses from Mass Spec that may represent crosslinked products
Input one mass per line

Input Control Masses: 
Masses observed in control experiments (for example with no crosslinker added) which can be eliminated from consideration
Input one mass per line


Select Mass Specificity:
Select Mass Specificity for finding a match between experimental and theoretical masses (in Daltons):
based on instrument precision and tolerance for error
Daltons
Select Cross Linker:

Questions and comments to Gerald J. Wyckoff and Owen Nadeau at: wyckoffg@umkc.edu and onadeau@kumc.edu